Applying basic theories to industrial practices in pharmaceutical development, this Second Edition explains how new and emerging technologies are utilized in the production of pharmaceutical granulation-demonstrating cost-effective strategies to manufacture solid-dosage forms with consistent physical properties while complying with current regulatory requirements.

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The `plant’ is often the most neglected part of plant-based medicine. Throughout time, humans have searched, collected, and effectively used plants for healing. Currently, the medicinal plant-based business is flourishing at a dramatic pace and at the expense of an already declining population of plant species, many of which are on the verge of extinction. In spite of this history and popularity, the mystery of what transforms a plant into a medicinal plant persists, and there are chronic problems with ensuring the safety and efficacy of medicinal plant products. Therefore, there is a real need for a full characterization of medicinal plant species and for the development and application of novel technologies for the production of plant-based medicines. This book highlights some of the recent advances and new approaches to the development of technologies for plant-based medicines and is intended to stimulate new discussions among researchers, regulatory authorities, and pharmaceutical organizations, leading to significant advancements in the field.

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Rang & Dale’s Pharmacology provides you with all the knowledge you need to get through your pharmacology course and beyond. Drs. Humphrey P. Rang, Maureen M. Dale, James M. Ritter, Rod Flower, and Graeme Henderson present a clear and accessible approach to the analysis of therapeutic agents at the cellular and molecular level through detailed diagrams, full-color illustrations, and pedagogical features. Plus, USMLE-style review questions and additional learning tools online at studentconsult.com make this the perfect resource to turn to for a full understanding of key concepts in pharmacology.

• Access the fully searchable text online at studentconsult.com, along with 500 USMLE-style multiple-choice review questions, downloadable images, and online only references.
• Find and cross-reference information quickly using a color-coded layout that makes navigation easy.
• Effectively understand and review key concepts through detailed diagrams and full-color illustrations that clarify even the most complex concepts.
• Reinforce your learning with key points boxes and clinical uses boxes that highlight crucial information and clinical applications.

• Apply current best practices and clinical applications through thoroughly updated and revised drug information.
• Stay current with the latest developments in the field thanks to major updates in chapters such as How Drugs Act; Amino Acid Transmitters; Analgesic Drugs; Antidepressant Drugs; and Drug Addiction, Dependence & Abuse.
• Tap into comprehensive content tailored to your courses with new and reorganized chapters on Host Defense; Inflammatory Mediators; Pharmacogenetics, Pharmacogenomics & Personalized Medicine; Hydroxytoptomine & The Pharmacy of Migraine; and Purines.

Build your basic and clinical pharmacology knowledge with a comprehensive yet easy-to-use text

List Price: $ 71.95

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Various pharmaceutical nanocarriers, such as nanospheres, nanocapsules, liposomes, micelles, cell ghosts, lipoproteins and some others are widely used for experimental (and already clinical) delivery of therapeutic and diagnostic agents. The use of nanoparticulate pharmaceutical carriers to enhance the in vivo efficiency of many drugs well established itself over the past decade both in pharmaceutical research and clinical setting. Looking into the future of the field of drug delivery, we have to think about the development of the next generation of pharmaceutical nanocarriers combining the whole variety of properties and allowing for the simultaneous performance of multiple functions. Surface modification of pharmaceutical carriers is often used to control their properties in a desirable fashion and make them to simultaneously perform several different functions. This book is all about these futuristic multifunctional medicines.

Multifunctional Pharmaceutical Nanocarriers intends to bring together the experts in the field of multifunctional nanopharmaceuticals to provide the reader with the cutting edge information, a critical overview of the field, and analysis of the current and future tendencies and developments to aid in the rapid developments in the field.

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Furnishing the latest interdisciplinary information on the most important and frequently the only investigational system available for discovery programs that address the effects of small molecules on newly discovered enzyme and receptor targets emanating from molecular biology, this timely resource facilitates the transition from classical to high throughput screening (HTS) systems and provides a solid foundation for the implementation and development of HTS in bio-based industries and associated academic environments.

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An indispensable resource for busy researchers

Your time is valuable-too valuable to spend hunting through the technical literature in search of the right HPLC assay techniques for your projects. With HPLC Methods for Recently Approved Pharmaceuticals, you’ll quickly identify and replicate the ideal procedures for your project needs, without having to refer to original source publications. More of your time can then be spent in the lab, not the library.

Covering the relevant world literature through 2003, this book picks up where Dr. Lunn’s acclaimed HPLC Methods for Pharmaceutical Analysis left off. It arms you with established HPLC assay techniques for hundreds of newly approved drugs, as well as drugs for which assay methods were only recently developed. Combining detailed descriptions of procedures with specially annotated references, this practical handbook gives you:
* HPLC methods for 390 commonly prescribed pharmaceutical compounds
* Various procedures for each drug listed together-making it easy to mix and match for customized approaches
* Methods for drugs in biological fluids and for bulk and formulated drugs
* Chemical structures, molecular weights and formulas, and CAS Registry Numbers
* Cross-references to The Merck Index
* Retention times of other drugs that can be assayed using the same methods

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Encapsulated cells offer enormous potential for the treatment of human disease. The “artificial barriers” which protect living cells from the hostile immunological environment of the recipient, are an important component in transplantation of human and animal tissue. “Cell Encapsulation Technology and Therapeutics” features in-depth reviews of all major cell encapsulation systems, as well as underlying engineering principles and mass transfer theory. The book includes detailed descriptions of chemical properties of encapsulation matericals, purification, biocompatibility issues and experimental protocols. The broad application spectrum of cell encapsulation is highlighted with chapters on topics ranging from artificial organs such as pancreas, parathyroid, liver and kidney, to central nervous system applications, hemophelia, growth hormone, lysosomal storage disease, the encapsulation of embryos and plant cells, as well as advanced cell culture in bioreactors. “Cell Encapsulation Technology and Therapeutics” is a comprehensive reference work written by a team of international experts. In addition to being a source of practical information for scientists working in the field of cell encapsulation, it will interest biotechnological and pharmaceutical researchers.

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The self-assembly of synthetic surfactants and other non-phospholipids into vesicles was initial studied in the 1970s by cosmetic scientists when non-ionic surfactant vesicles or niosomes were reported. Considering that this time a big body of study has sought to define these systems primarily as drug carriers and also as characteristics of interest to the colloid scientist. Synthetic surfactant vesicles, as the name implies, could also be fabricated from a vast array of amphiphiles, including a number of pharmaceutically acceptable supplies. They could also be ready in a assortment of shapes and sizes and have a number of applications. This book is developed to serve as an introductory text to the science of non-phospholipid vesicles and will be of use to colloid, drug delivery, cosmetic, and materials scientists. It aims to acquaint the reader with the physicochemistry and biomedical applications of these synthetic surfactant non-phospholipid vesicles. Component 1 introduces the reader to physicochemical aspects of the

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Millennium Pharmaceuticals, Inc., Cambridge, MA. Text provides formulas and procedures for determining the appropriate sample size for testing equality. Presents various statistical procedures, current regulatory requirements, methodology for design and analysis, and recent developments in clinical research.

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